2018

Vemu A, Szczesna E, Zehr EA, Spector JO, Grigorieff N, Roll-Mecak A, Deaconescu AM | 2018 | Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation | Vemu_Science2018.pdf - 17.69 MB
Grant T, Rohou A, Grigorieff N | 2018 | cisTEM, User-friendly software for single-particle image processing | Grant_eLife2018.pdf - 2.76 MB
Close W, Neumann M, Schmidt A, Hora M, Annamalai K, Schmidt M, Reif B, Schmidt V, Grigorieff N, Fändrich M | 2018 | Physical basis of amyloid fibril polymorphism | Close_NatureComm2018.pdf - 4.57 MB
Regan MC, Grant T, McDaniel MJ, Karakas E, Zhang J, Traynelis SF, Grigorieff N, Furukawa H | 2018 | Structural mechanism of functional modulation by gene splicing in NMDA receptors | Regan_Neuron2018.pdf - 4.69 MB
Zehr EA, Rohou A, Liu Y, Verba KA, Pogliano J, Grigorieff N, Agard DA | 2018 | Mechanistic origins of dynamic instability in filaments from the phage tubulin, PhuZ | Zehr_bioRxiv2018.pdf - 18.46 MB
Liberta F, Loerch S, Rennegarbe M, Schierhorn A, Westermark P, Westermark GT, Grigorieff N, Fändrich M, Schmidt M | 2018 | Cryo-EM structure of an amyloid fibril from systemic amyloidosis | Liberta_bioRxiv2018.pdf - 13.13 MB
Bartesaghi A, Aguerrebere C, Falconieri V, Banerjee S, Earl LA, Zhu X, Grigorieff N, Milne JLS, Sapiro G, Wu X, Subramaniam S | 2018 | Atomic resolution cryo-EM structure of β-galactosidase | Bartesaghi_Structure2018.pdf - 19.57 MB

2017

Loveland AB, Demo G, Grigorieff N, Korostelev AA | 2017 | Ensemble cryo-EM elucidates the mechanism of translation fidelity | Loveland_Nature2017.pdf - 22.5 MB
Liu Y, Pan J, Jenni S, Raymond DD, Caradonna T, Do KT, Schmidt AG, Harrison SC, Grigorieff N | 2017 | CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface | Liu_JMB2017.pdf - 2.14 MB
Demo G, Rasouly A, Vasilyev N, Svetlov V, Loveland AB, Diaz-Avalos R, Grigorieff N, Nudler E, Korostelev AA | 2017 | Structure of RNA polymerase bound to ribosomal 30S subunit. | Demo_eLife2017b.pdf - 3.31 MB
Aberyrathne PD, Grigorieff N | 2017 | Expression, purification, and contaminant detection for structural studies of Ralstonia metallidurance ClC protein rm1 | Abeyrathne_PLoS2017.pdf - 22.76 MB
Liu Y, Pan J, Cai Y, Grigorieff N, Harrison SC, Chen B | 2017 | Conformational states of a soluble, uncleaved HIV-1 envelope trimer | Liu_JVirol2017.pdf - 3.35 MB
Rickgauer JP, Grigorieff N, Denk W | 2017 | Single-protein detection in crowded molecular environments in cryo-EM images | Rickgauer_eLife2017.pdf - 3.75 MB
Demo G, Svidritskiy E, Madireddy R, Diaz-Avalos R, Grant T, Grigorieff N, Sousa D, Korostelev AA | 2017 | Mechanism of ribosome rescue by ArfA and RF2 | Demo_eLife2017a.pdf - 6.02 MB

2016

Tajima N, Karakas E, Grant T, Simorowski N, Diaz-Avalos R, Grigorieff N, Furukawa H | 2016 | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil | Tajima_Nature2016.pdf - 11.13 MB
Aberyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA | 2016 | Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome | Abeyrathne_eLife2016.pdf - 9.56 MB
Laxmikanthan G, Xu C, Brilot AF, Warren D, Steele L, Seah N, Tong W, Grigorieff N, Landy A, Van Duyne GD | 2016 | Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction | Laxmikanthan_eLife2016.pdf - 6.81 MB
Grigorieff N | 2016 | Frealign: An exploratory tool for single-particle cryo-EM | Grigorieff_MethodsEnzymology2016.pdf - 2.64 MB
Schmidt A, Annamalai K, Schmidt M, Grigorieff N, Fändrich M | 2016 | Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril | Schmidt_PNAS2016.pdf - 3.15 MB
Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF, Grigorieff N, Korostelev AA | 2016 | Ribosome•RelA structures reveal the mechanism of stringent response activation | Loveland_eLife2016.pdf - 4.96 MB
Oldham ML, Grigorieff N, Chen J | 2016 | Structure of the transporter associated with antigen processing trapped by herpes simplex virus | Oldham_eLife2016.pdf - 5.54 MB

2015

Liang B, Li Z, Jenni S, Rahmeh AA, Morin BM, Grant T, Grigorieff N, Harrison SC, Whelan SPJ | 2015 | Structure of the L protein of vesicular stomatitis virus from electron cryomicroscopy | Liang_Cell2015.pdf - 9.4 MB
Grant T, Grigorieff N | 2015 | Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6 | Grant_eLife2015.pdf - 4.38 MB
Chiu P-L, Li X, Li Z, Beckett B, Brilot AF, Grigorieff N, Agard DA, Cheng Y, Walz T | 2015 | Evaluation of super-resolution performance of the K2 electron-counting camera using 2D crystals of aquaporin-0 | Chiu_JSB2015.pdf - 6.28 MB
Schmidt M, Rohou A, Lasker K, Yadav JK, Schiene-Fischer C, Fändrich M, Grigorieff N | 2015 | Peptide Dimer Structure in an Aβ(1-42) Fibril Visualized with Cryo-EM | Schmidt_PNAS2015.pdf - 2.25 MB