VP6 at 3.8 Å

A three-dimensional reconstruction of VP6, one of the rotavirus capsid proteins, at 3.8-Å resolution. This structure was obtained by cryo-EM and single-particle analysis; 8,400 images of rotavirus particles were processed, and icosahedral symmetry and nonicosahedral symmetry were imposed to achieve a high degree of averaging. Many side chains of amino acids are visible.

From Zhang, X., Settembre, E., Xu, C., Dormitzer, P.R., Bellamy, R., Harrison, S.C., and Grigorieff, N. 2008. PNAS 105:1867–1872. © 2008 by the National Academy of Sciences.