Nanoscale flexibility parameters of Alzheimer amyloid fibrils determined by electron cryo-microscopy
Publication Type
Journal Article
Year of Publication
2010
Refereed Designation
Refereed
Journal
Angew Chem Int Ed Engl
Volume
49
Pagination
1321-1323
Date Published
2010 Jan 12
Citation Key
447
Keywords
Alzheimers disease, amyloids, electron microscopy, nanotechnology, Protein Folding
Abstract
Versatile nanomaterial: Unusually high nanoscale flexibility was displayed by amyloid fibils in electron microscopy studies (see picture). This finding is relevant for understanding amyloid pathogenicity and for potential biotechnological applications.
